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Description
Separate proteins and their variants using Thermo Scientific™ ProPac™ SCX-10 LC Columns, which provide exceptionally high resolution. Based on stationary phases composed of 10μm nonporous polymeric beads, ProPac columns resolve isoforms that differ by a single charged residue. A thin, hydrophilic layer grafted to the particle core eliminates unwanted secondary interactions. The cation-exchange surface provides pH-based selectivity control and fast mass transfer for high-efficiency separation and moderate capacity.
- Nonporous core particle results in high-efficiency peaks and high-resolution separations of protein variants
- Hydrophilic layer prevents unwanted secondary interactions
- Grafted cation-exchange surface provides pH-based selectivity control and fast mass transfer for high-efficiency separation and moderate capacity
- Useful for characterization of related protein variants
Specifications
Semi-Preparative Column | |
1 mL/min | |
3000 psi (200 bar) | |
10 μm | |
Nonporous | |
Sulfonate | |
Spherical, Nonporous Polymer | |
Ion Exchange |
22 mm | |
250 mm | |
pH 2 to 12, 80% compatible with acetonitrile, acetone, methanol, compatible with nonionic and zwitterionic detergents, incompatible with cationic detergents | |
2 to 12 | |
60°C | |
ProPac | |
Ion Exchange | |
Bio-LC |
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