Thermo Scientific Chemicals Ingenol 3-angelate, 98%

Description

 

Ingenol 3-Angelate is used as a PKC activator, anticancer, and immunostimulant compound. It is also used to exhibits antileukemic activity, induces nuclear translocation of PKCδ, and induces apoptosis in acute myeloid leukemia (AML) cell lines and primary AML blast cells. Also displays antiproliferative effects and induces apoptosis in Colo205 cells.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Specifications

Chemical Identifiers

• CAS: 75567-37-2
• Molecular Formula: C25H34O6
• Molecular Weight (g/mol): 430.54
• InChI Key: VDJHFHXMUKFKET-WDUFCVPESA-N
• IUPAC Name: (1S,4S,5S,6R,9S,10R,12R,14R)-5,6-dihydroxy-7-(hydroxymethyl)-3,11,11,14-tetramethyl-15-oxotetracyclo[7.5.1.0¹,⁵.0¹⁰,¹²]pentadeca-2,7-dien-4-yl (2Z)-2-methylbut-2-enoate
• SMILES: C\C=C(\C)C(=O)O[C@H]1C(C)=C[C@@]23[C@H](C)C[C@@H]4[C@H]([C@H](C=C(CO)[C@@H](O)[C@]12O)C3=O)C4(C)C

• Quantity: 1 mg
• Description: White to off-white
• Content And Storage: -30°C to -10°C
• For Use With (Application): Protein kinase C activator
• Formula Weight: 348.40
• Product Type: Ingenol 3-angelate, 98%
• Form: Powder
• Assay: 98%

Safety and Handling

Recommended Storage

Store at -20°C

SDS

RUO – Research Use Only