CHAPS, 98+%, Thermo Scientific Chemicals

Description

CHAPS, >-98%, C32H58N2O7S, CAS Number-75621-03-3, 3-[(3-Cholamidopropyl)dimethylammonio]-1-propanesulfonate, 25g, 614.88, H315-H319-H335, GHS H Statement H315-H319-H335 Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Buffer; zwitterionic nondenaturing detergent for solubilizing membrane proteinsCHAPS is used in the laboratory to dissolve biological macromolecules such as proteins. It acts as a non-denaturing solvent used in purification of membrane proteins. It is also useful in conjunction with nonionic detergents like Triton X-100. Further, it is used as a non-denaturing zwitterionic detergent for membrane biochemistry.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Buffer; zwitterionic nondenaturing detergent for solubilizing membrane proteinsCHAPS is used in the laboratory to dissolve biological macromolecules such as proteins. It acts as a non-denaturing solvent used in purification of membrane proteins. It is also useful in conjunction with nonionic detergents like Triton X-100. Further, it is used as a non-denaturing zwitterionic detergent for membrane biochemistry.

Solubility
Slightly soluble in water.

Notes
Store in a cool. Incompatible with oxidizing agent, strong acid and bases.

Specifications

Chemical Identifiers

• CAS: 75621-03-3
• Molecular Formula: C32H58N2O7S
• Molecular Weight (g/mol): 614.883
• MDL Number: MFCD00012116
• InChI Key: UMCMPZBLKLEWAF-GBSSQDIOSA-N
• Synonym: 3-[(3-Cholamidopropyl)dimethylammonio]-1-propanesulfonate
• PubChem CID: 134129639
• IUPAC Name: 3-[dimethyl-[3-[[(4R)-4-[(3R,5S,7R,8R,9R,10S,12S,13R,14R,17S)-3,7,12-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl]amino]propyl]azaniumyl]propane-1-sulfonate
• SMILES: CC(CCC(=O)NCCC[N+](C)(C)CCCS(=O)(=O)[O-])C1CCC2C1(C(CC3C2C(CC4C3(CCC(C4)O)C)O)O)C

• Melting Point: 156°C to 158°C (decomposition)
• Quantity: 5 g
• Solubility Information: Slightly soluble in water.
• Formula Weight: 614.88
• Percent Purity: ≥98%
• Chemical Name or Material: CHAPS

Safety and Handling

Hazard Category	H315-H319-H335
Hazard Statement	GHS H Statement H315-H319-H335 Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statement	P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c
TSCA	No
Recommended Storage	Ambient temperatures; Store under Nitrogen

SDS

RUO – Research Use Only