Aneuploidy Detection
Support Your Research and Detect Abnormalities
Gain important insights with Ion™ ReproSeq™ kits for preimplantation genetic testing of aneuploidy (PGT-A), which leverage the speed and reliability of Ion Torrent™ Next-Generation Sequencing (NGS) systems. Detect chromosomal abnormalities, mosaic events, and small copy number variants (CNVs), from just 6 pg of DNA collected from a biopsy sample or spent culture media.
Enjoy a Simple, Rapid Workflow
With Ion ReproSeq PGS kits, you’ll go from cell to analysis in as little as 10 hours.* They include all the materials for library construction, template preparation, and sequencing on Ion Torrent NGS systems. They may also help you conduct your PGT research more quickly and help reduce user errors with the straightforward user interface, simple loading of reagent cartridges, and automated template preparation.
Enhance Your Analysis with SNP-Based QC
Enable germline single-nucleotide polymorphism (SNP) detection from embryo biopsy samples with the Ion AmpliSeq™ Polyploidy Panel kit, available as an add-on to Ion ReproSeq PGS kits. Unlock genomic variations unique to each sample for premium PGT-A analysis.
SNP-based QC features available with the kit include:
- Triploidy (69,XXX) identification
- Maternal contamination risk assessment
- Sibling sample tracking
Analyze PGT-A and PGT-M Simultaneously
Harnessing the power of NGS technology, Ion ReproSeq and Ion Torrent™ PGD-SEQ™ kits require only a single sample to detect both PGT-A and monogenic disorders (PGT-M) simultaneously within a simplified and integrated Ion GeneStudio™ S5 System workflow.
Maximize Your Productivity
Simplify templating, sequencing, analyzing, and reporting for your PGT-A workflow with the Ion Torrent Genexus™ Integrated Sequencer. Perform premium PGT-A by combining Ion ReproSeq with Polyploid Panel Kits, available for 192 or 384 samples. Get results in under 11 hours for spent cell culture media or up to 48 embryo biopsy samples.
Experience Fast, Focused, and Scalable NGS
Engage in simple, sample-to-data workflows for targeted sequencing with Ion GeneStudio S5 Systems, which can elevate your processes with speed and scalability. Choose from five Ion S5™ chip options that enable a sequencing throughput range of 2 M to 130 M reads per run.
For even faster data collection and less hands-on time, combine GeneStudio S5 Systems with the Ion Chef™ System. Ion Chef is a complete solution featuring a walk-away workflow—requiring less than 45 minutes of hands-on time—that includes automated Ion AmpliSeq library preparation as well as reproducible template preparation and chip loading. Along with the other Ion Torrent NGS workflows, it is backed by application-specific analysis and reporting solutions.
For Research Use Only. Not for use in diagnostic procedures.
*Turnaround time for the Ion ReproSeq PGS Kit with Ion 510 Chips (16 samples/run) is typically less than 10 hours with less than 2 hours of hands-on time.