Thermo Scientific™ ProPac™ SAX-10 HPLC Columns

Catalog Number	Mfr. No.	Particle Size	Diameter (Metric)	Length (Metric)	Column Format
DX054997	Thermo Scientific™ 054997	10 μm	4 mm	250 mm	Analytical Column
DX063448	Thermo Scientific™ 063448	10 μm	2 mm	250 mm	Analytical Column
03-254-046	Thermo Scientific™ 088770	10 μm	22 mm	250 mm	Semi-Preparative Column
DX054998	Thermo Scientific™ 054998	10 μm	4 mm	50 mm	Guard Column
03-254-082	Thermo Scientific™ 063454	10 μm	2 mm	50 mm	Guard Column
DXSP5730	Thermo Scientific™ 088775	10 μm	4 mm	250 mm	3 Lots of Resin, 1 Column / Lot (3 Columns)
DX078990	Thermo Scientific™ 078990	10 μm	4 mm	50 mm	Analytical Column

Description

Use Thermo Scientific™ ProPac™ SAX-10 LC Columns for exceptionally high resolution and efficiency when separating protein variants. Based on a nonporous 10μm core particle that provides pressure stability, ProPac columns can resolve isoforms that differ by a single charged residue. A thin, hydrophilic layer prevents unwanted secondary interactions. The grafted anion-exchange surface provides pH-based selectivity control and fast mass transfer for high-efficiency separation and moderate capacity.

Maximizing Resolution

• ProPac SAX-10 LC column is a strong anion-exchanger with a quaternary amine functional group.
• Column sizes range from 2mm I.D., for analytical work, up to 22mm I.D. for semiprep work.

Superior Performance for Protein Analysis

• Ideal for characterization and quality control assessment of closely-related protein variants
• Unequaled high-resolution separations
• High-efficiency peaks with excellent recovery
• Higher capacity than other columns based on nonporous particles
• Superior column-to-column and lot-to-lot reproducibility eliminates column variability as a concern in stability and QA/QC testing

Specifications

• Particle Size: 10 μm
• Pore Size: Nonporous
• Stationary Phase: Quaternary Ammonium
• Column Type: Ion Exchange

• pH: 2 to 12
• Temperature: 60°C
• Packing Material: Spherical, Nonporous Polymer
• Phase: Ion Exchange

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