Applied Biosystems Capillary Electrophoresis Genetic Analyzers and Consumables

Sanger sequencing is used to study a small subset of genes linked to a defined phenotype, confirm next-generation sequencing (NGS) variants, detect minor allele fractions down to 5%, or read contiguous sequences up to 1,000 bases.

Fragment analysis is a powerful technique with simple, straightforward workflows. It’s used in a range of applications such as detection of mutations, genotyping, identification of short tandem repeats, and gene expression profiling.

Applied Biosystems™ genetic analysis systems and consumables such as Applied Biosystems™ Big Dye™ products, POP polymers, and clean-up products are trusted standards for Sanger sequencing and fragment analysis by capillary electrophoresis. They’re proven through decades of results, including the first sequencing of the human genome and the discovery of genes implicated in diseases like cystic fibrosis.

Financing Programs

Low APR Financing

Thermo Fisher Scientific offers financing options to help you acquire the products and equipment you need.

Trade-In/Trade-Up Program

Technology keeps progressing. As the world leader in serving science, Thermo Fisher Scientific is committed to keeping your research and results on pace. Trade in or trade up your current equipment or instrumentation to upgrade to the latest technology.

Ask your Fisher Scientific sales representative about financing options and the Trade-In/Trade-Up program to learn more.

Capillary Electrophoresis Applications

Plasmid Sequencing

Accurately analyze subcloned inserts with read lengths ranging from <300 bp to >600 bp.

Species Identification

Identify bacterial 16s rRNA with access to the groundbreaking phylogenetic research work of Carl Woese et al.

CRISPR-Cas9 Gene Editing

Evaluate the efficiency of CRISPR events, quantify gene editing activity (target region analyzed using TIDE software), characterize the gene target in cell lines, assess gene copy number, and more.

Cell Line Authentication (CLA)

Confidently detect contaminating cell lines with sensitivity and accuracy.

SNP Genotyping

The Applied Biosystems™ SNaPshot™ Multiplex System saves time with built-in reporting of fragment analysis and by combining sequencing and fragment analysis on the same plate during the same run.

MLPA

Analyze human copy number variation (CNV) with Multiplex Ligation-Dependent Probe Amplification (MLPA™).

Oncology Research

Confirm next-generation sequencing.

"The SeqStudio instrument was very easy to set up in the lab; it did not require us to have a lot of initial expertise because the instrument is extremely easy to handle. By using the RAS panel, we found very consistent results across the different platforms that we used, whether it was the Sanger platform or the NGS platform."

Dr. Luca Quagliata, Senior Director of the Contract R&D Unit at the Institute of Medical Genetics and Pathology, University Hospital of Basel, Switzerland