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  7. Sunitinib malate, Tocris Bioscience™

Sunitinib malate, Tocris Bioscience™

Catalog Number 376850
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
341031-54-7
C26H33FN4O7
532.569
LBWFXVZLPYTWQI-ZHUJRYRNSA-N
sunitinib malate, malic acid; sunitinib
53386275
N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fluoro-2-oxo-1H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide;(2R)-2-hydroxybutanedioic acid
CCN(CC)CCNC(=O)C1=C(NC(=C1C)C=C2C3=C(C=CC(=C3)F)NC2=O)C.C(C(C(=O)O)O)C(=O)O
This item is not returnable. View return policy
341031-54-7
C26H33FN4O7
532.569
LBWFXVZLPYTWQI-ZHUJRYRNSA-N
sunitinib malate, malic acid; sunitinib
53386275
N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fluoro-2-oxo-1H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide;(2R)-2-hydroxybutanedioic acid
CCN(CC)CCNC(=O)C1=C(NC(=C1C)C=C2C3=C(C=CC(=C3)F)NC2=O)C.C(C(C(=O)O)O)C(=O)O

Description

Potent VEGFR, PDGFRβ and KIT inhibitor

Potent, ATP-competitive VEGFR, PDGFRβ and KIT inhibitor (Ki values are 2, 9, 17, 8 and 4 nM for VEGFR -1, -2, -3, PDGFRβ and KIT respectively). Also inhibits cellular receptor phosphorylation of FLT3, RET and CSF-1R. Exhibits antiangiogenic and antitumor activity in multiple xenograft models.
Quantity 50 mg
Formula Weight 532.56
Percent Purity >99%
Chemical Name or Material Sunitinib malate

Safety and Handling

Recommended Storage Store at +4°C
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