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PI 103 hydrochloride, Tocris Bioscience™
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Quantity:
1 mg
10 mg
Description
Inhibitor of DNA-PK, PI 3-kinase (p110α) and mTOR (IC50 values are 2, 8, 20, 26, 48, 83, 88, 150, 850, 920, ∽ 1000 and 2300 nM for DNA-PK, p110α, mTORC1, PI 3-KC2β, p110δ, mTORC2, p110β, p110γ, ATR, ATM, PI 3-KC2α and hsVPS34 respectively). Inhibits growth of human tumor xenografts in mice in vivo. Induces autophagosome formation in glioma cells.
Specifications
Quantity | 10 mg |
Formula Weight | 384.82 |
Percent Purity | >98% |
Chemical Name or Material | PI 103 hydrochloride |
Safety and Handling
Recommended Storage | Desiccate at +4°C |
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