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Tocris Bioscience™ GSK 2606414
Potent and selective PERK inhibitor; orally bioavailable
$420.00 - $1754.00
Specifications
Purity | >99% |
---|---|
Product Type | GSK 2606414 |
Molecular Weight (g/mol) | 451.44 |
Inhibitors | GSK 2606414 |
Description
Potent and selective protein kinase R-like ER kinase (PERK) inhibitor (IC50 = 0.4 nM). Exhibits >1000-fold selectivity for PERK over HR1 and PKR. Inhibits thapsigargin-induced PERK phosphorylation in lung carcinoma A549 cells. Attenuates subcutaneous pancreatic human tumor xenograft growth in mice. Orally bioavailable.Specifications
>99% | |
GSK 2606414 | |
451.44 | |
GSK 2606414 |
For Research Use Only
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