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Tocris Bioscience™ Geldanamycin

Selective Hsp90 inhibitor

Supplier:  Tocris Bioscience™ 1368/1

Catalog No. 13-681-R


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Description

Description

Selectively inhibits heat shock protein 90 (Hsp90). Binds to the ATP site of Hsp90 (Kd = 1.2 μM) and inhibits its chaperone activity. Consequently inhibits activities of oncogenic kinases (e.g. src, Raf), p53 and steroid receptors. Demonstrates antiproliferative effect on breast cancer stem-like cells.
Specifications

Specifications

1 mg
>98%
C29H40N2O9
Soluble to 10 mM in DMSO
Desiccate at -20°C
30562-34-6
560.64g/mol
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